Regenerative therapy is a relatively new branch of medicine. The technique relies on the body's own source of cells that physiologically cannot reach damaged joint structures. Using specific regenerative medicine procedures, cells with regenerative potential are harvested and injected into the joint where, through proliferation or production of growth factors, they will restore joint components, restoring functionality in the absence of painful symptoms.


The transfer of regenerative cells from adipose tissue is one of the procedures that stop degeneration by restoring joint structures, removing pain and restoring functionality, so that the patient can resume daily activities in comfort.


The procedure is minimally invasive, is performed in the clinic in a relatively short time (two to three hours), using only local anesthesia, and the patient can go home immediately after surgery.


The technique of regenerative cell transfer from adipose tissue can be performed at any age; it postpones and even cancels joint replacement surgery.


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Joint pathology degenerative includes the spectrum of painful joint symptoms and associated dysfunctionality and is based on the destruction of joint structures: synovial membrane, cartilage, bone, ligaments. Damage to joint structures is no longer the prerogative of old age, but can start at any age.
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Causes can be multiple: inflammatory, traumatic (overuse, accidents) or metabolic. Therefore, the procedures used in regenerative medicine are aimed at people with degenerative pathology of any age (>18 years), athletes (hobby or performance), patients with inflammatory degenerative diseases, patients who have suffered trauma (accidents or overstrain), etc.


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1. ASC technique:

transfer of a quantity of adipose material (corresponding to the targeted joint volume), mechanically processed in a closed, sterile space, adipose material harvested by liposuction by the plastic surgeon (abdominal area, outer thighs). Here we find a sufficient quantity of regenerative cells: between 500-900 thousand cells/ml.

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2. SVF technique:

harvesting a much larger amount of adipose tissue (10x
>ASC), mechanical processing and centrifugation (after liposuction) will
leads to a number of regenerative cells 4X> than the number of
obtained by the ASC technique.

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3. SVF HIBRID technique:

uses approx. 120 ml adipose tissue, harvested by
liposuction, followed by mechanical processing in a closed, sterile space and a
specific centrifugation will result in a number of regenerative cells
of 10X>decade ASC. This technique is unique in Romania and can
perform exclusively at Cronosmed. The technique ensures, in addition to a very
of regenerative cells, their viability and ability to adhere to the
joint structures.


After surgery for the transfer of regenerative cells from adipose tissue, the rebuilding of joint structures takes time, i.e. three to four months, until
at most one year. The recovery of the benefits acquired by the patient using this procedure depends on several factors (patient compliance with supportive therapies, patient's daily activity, patient's age and initial stage of degeneration) but it is estimated that the procedure needs to be repeated every 6-10 years.


The results of such an intervention depend on:


  • Etiology of joint degeneration (presence of an autoimmune inflammatory disease - rheumatoid arthritis, peripheral spondylitis - requires special therapeutic approach).
  • Stage of degeneration (regenerative cell transfer will have a dramatic result in the early stages of degeneration
  • Patient age (younger patients will achieve significantly better results than older patients)
  • Existing co-morbidities (a metabolic pathology can slow down the regeneration process)
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